Sara S Bashraheel Selected Research

gamma-Glutamyl Hydrolase (Carboxypeptidase G2)

2/2020	In vitro studies on CNGRC-CPG2 fusion proteins for ligand-directed enzyme prodrug therapy for targeted cancer therapy.
4/2019	Production of "biobetter" variants of glucarpidase with enhanced enzyme activity.
1/2019	Production of "biobetter" glucarpidase variants to improve drug detoxification and antibody directed enzyme prodrug therapy for cancer treatment.
1/2018	Isolation and molecular characterization of novel glucarpidases: Enzymes to improve the antibody directed enzyme pro-drug therapy for cancer treatment.

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Sara S Bashraheel Research Topics

Disease

6	Neoplasms (Cancer) 05/2020 - 01/2018
1	Hypotension (Low Blood Pressure) 07/2019
1	Sepsis (Septicemia) 07/2019

Drug/Important Bio-Agent (IBA)

4	EnzymesIBA 02/2020 - 01/2018
4	gamma-Glutamyl Hydrolase (Carboxypeptidase G2)IBA 02/2020 - 01/2018
4	ProdrugsIBA 02/2020 - 01/2018
3	Pharmaceutical PreparationsIBA 02/2020 - 01/2019
3	Methotrexate (Mexate)FDA LinkGeneric 02/2020 - 01/2018
3	glucarpidaseIBA 04/2019 - 01/2018
2	LigandsIBA 05/2020 - 02/2020
2	CytokinesIBA 05/2020 - 07/2019
2	SuperantigensIBA 05/2020 - 07/2019
1	Immune Checkpoint InhibitorsIBA 05/2020
1	DisulfidesIBA 02/2020
1	asparagine-glycine-arginineIBA 02/2020
1	ZD 2767IBA 02/2020
1	Proteins (Proteins, Gene)FDA Link 02/2020
1	CD13 Antigens (Alanine Aminopeptidase)IBA 02/2020
1	Cysteine (L-Cysteine)FDA Link 02/2020
1	AntigensIBA 07/2019
1	Peptides (Polypeptides)IBA 07/2019
1	EpitopesIBA 01/2018

Therapy/Procedure

5	Therapeutics 05/2020 - 01/2018
1	Precision Medicine 05/2020
1	Immunotherapy 07/2019